- *Season Premiere* – Chuck – NBC @ 8/7c
- *Season Premiere* – Life – NBC @ 10/9c
- *Sports* – Monday Night Football: Baltimore Ravens at Pittsburgh Steelers – ESPN @ 8:30/7:30c
- *New* – Boston Legal – ABC @ 10/9c
- *New* – Charlie Jade – SciFi @ 3AM/2AMc (Monday night/Tuesday morning)
- *New* – CSI: Miami – CBS @ 10/9c
- *New* – Dancing With the Stars – ABC @ 8/7c (2-Hour New Episode)
- *New* – Dr. 90210 – E! @ 10/9c
- *New* – Gossip Girl – CW @ 8/7c
- *New* – Heroes – NBC @ 9/8c
- *New* – How I Met Your Mother – CBS @ 8:30/7:30c
- *New* – I Want to Work for Diddy – VH1 @ 9/8c
- *New* – Intervention – A&E @ 9/8c
- *New* – My Super Sweet 16 Presents: Exiled – MTV @ 10:30/9:30c
- *New* – One Tree Hill – CW @ 9/8c
- *New* – Paranormal State – A&E @ 10/9c
- *New* – Prison Break – FOX @ 9/8c
- *New* – Raising the Bar – TNT @ 9/8c
- *New* – Terminator: The Sarah Connor Chronicles – FOX @ 8/7c
- *New* – The Big Bang Theory – CBS @ 8/7c
- *New* – The Hills – MTV @ 10/9c
- *New* – Two and a Half Men – CBS @ 9/8c
- *New* – Worst Week – CBS @ 9:30/8:30c