- *Season Finale* – Entourage – HBO @ 10/9c
- *Season Finale* – True Blood – HBO @ 9/8c
- *Special* – 2008 American Music Awards – ABC @ 8/7c
- *Special* – 2008 American Music Awards Red Carpet Live! – ABC @ 7/6c
- *Special* – 24: Redemption – FOX @ 8/7c (2-Hour Special)
- *Special* – A Colbert Christmas: The Greatest Gift of All – Comedy Central @ 10/9c (1-Hour Special)
- *Sports* – Football Night In America – NBC @ 7/6c
- *Sports* – Sunday Night Football: Indianapolis Colts at San Diego Chargers – NBC @ 8:15/7:15c
- *New* – Brotherhood – Showtime @ 8/7c
- *New* – Californication – Showtime @ 10/9c
- *New* – Cities of the Underworld – History Channel @ 9/8c
- *New* – Cold Case – CBS @ 9/8c
- *New* – Dexter – Showtime @ 9/8c
- *New* – Rock of Love Girls: Charm School – VH1 @ 9/8c
- *New* – Skins – BBC America @ 10/9c
- *New* – Summer Heights High – HBO @ 10:30/9:30c
- *New* – The Amazing Race – CBS @ 8/7c
- *New* – The Girls Next Door – E! @ 10/9c
- *New* – The Life & Times of Tim – HBO @ 11/10c
- *New* – The Pick-Up Artist – VH1 @ 10/9c
- *New* – The Unit – CBS @ 10/9c