- *Series Premiere* – Into the Unknown with George Noory – SciFi @ 11/10c
- *Sports* – Football Night In America – NBC @ 7/6c
- *Sports* – Sunday Night Football: Dallas Cowboys at Washington Redskins – NBC @ 8:15/7:15c
- *Special* – TRL Finale Special – MTV @ 8/7c (150-Minute Special)
- *New* – American Dad – FOX @ 9:30/8:30c
- *New* – Brotherhood – Showtime @ 8/7c
- *New* – Brothers & Sisters – ABC @ 10:01/9:01c
- *New* – Californication – Showtime @ 10/9c
- *New* – Cities of the Underworld – History Channel @ 9/8c
- *New* – Cold Case – CBS @ 9/8c
- *New* – Desperate Housewives – ABC @ 9/8c
- *New* – Dexter – Showtime @ 9/8c
- *New* – Entourage – HBO @ 10/9c
- *New* – Extreme Makeover: Home Edition – ABC @ 8/7c
- *New* – Family Guy – FOX @ 9/8c
- *New* – King of the Hill – FOX @ 8:30/7:30c
- *New* – Rock of Love Girls: Charm School – VH1 @ 9/8c
- *New* – Skins – BBC America @ 10/9c
- *New* – Summer Heights High – HBO @ 10:30/9:30c
- *New* – The Amazing Race – CBS @ 8/7c
- *New* – The Girls Next Door – E! @ 10/9c
- *New* – The Life & Times of Tim – HBO @ 11/10c
- *New* – The Pick-Up Artist – VH1 @ 10/9c
- *New* – The Simpsons – FOX @ 8/7c
- *New* – The Unit – CBS @ 10/9c
- *New* – True Blood – HBO @ 9/8c